IN SITU TRANSPLANTATION OF ADIPOSE-DERIVED STEM CELLS VIA PHOTOACTIVATION IMPROVES GLUCOSE METABOLISM IN OBESE MICE

In situ transplantation of adipose-derived stem cells via photoactivation improves glucose metabolism in obese mice

Abstract Background Accumulating evidence suggests that enhanced adipose tissue macrophages (ATMs) are associated with metabolic disorders in obesity and type 2 diabetes.However, therapeutic persistence and reduced homing stem cell function following cell delivery remains a critical hurdle for the clinical translation of stem cells in current appro

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Erythropoietin couples hematopoiesis with bone formation.

It is well established that bleeding activates the hematopoietic system to regenerate the loss of mature blood elements.We have shown that hematopoietic stem cells (HSCs) isolated from animals challenged with an acute bleed eugenia topiary spiral regulate osteoblast differentiation from marrow stromal cells.This suggests that HSCs participate in bo

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